Damaged bones may heal faster in a gravitational condition similar to Earth’s gravity

X-ray human knee. Cartilage is present in the knee, hip and fracture repair site, etc. organization. The body will also use cartilage stem cells to repair damaged bones. According to foreign media reports, a new study pointed out that gravity and physical exercise may be the key to the healing of damaged bones. Successful long-term space trips – such as long journeys flying around the moon or going to Mars and beyond the planet – not only need to consider how to maintain the health of human travelers, but also the question of their treatment under the condition of degradation and injury The In this new study, the researchers focused on the repair of cartilage damage in space. Cartilage is present in the knee, hip and fracture repair site, etc. organization. “Cartilage tissue engineering has received a lot of attention because the cartilage as a bloodless tissue, no blood supply, so there is no renewable capacity,” the paper co-author, the University of Missouri School of Engineering Dean Elizabeth Loboa (Elizabeth Loboa) said, “If Someone in the space of fractures … … at both ends of the re-connection when the bone, after a new cartilage through the middle of the process, the bones to completely heal. “At present, many different disciplines of scientists are committed to the development of new technologies, Make long-term space travel a reality. Some people have studied how to grow crops in microgravity, while others are trying to build spacecraft that can fly long in space. Elizabeth Robera and two colleagues, Liliana Mellor and Andrew Steward, decided to study the formation of cartilage in microgravity. Microgravity is a kind of weightlessness experienced by astronauts in space free fall, which is very common in spacecraft – such as the International Space Station. Long-term space flight astronauts to maintain health, it must develop physical strength, to maintain the state of the musculoskeletal system, and repair any damage. Chondrocytes are the only cells in cartilage that are indispensable to maintain joint activity; the body also produces cartilage stem cells that promote the healing of broken bones. Astronauts who perform long-term space missions are faced with a variety of environmental conditions that are detrimental to cartilage health, and one of them is microgravity. Sunny Williams (Sunni Williams) in the International Space Station installed on the first treadmill exercise. Today, the international space station used by the treadmill named CLOBERT – to American comedian and satirist Stephen Cole (often translated as a bear bear) named to help astronauts to keep the bones, muscles and cardiovascular health. Astronaut Scott Kelly lived on the International Space Station for nearly a year. A research team found that when Kelly spent six months in space, his bone formation rate has declined. In a no-gravity environment, Kelly and other astronauts exercise about two hours a day to avoid muscle atrophy and osteoporosis. In order to stay healthy, their bodies need to imitate the walking posture and other daily activities on the surface of the earth by gravity. This process is called “stress load”, similar to the exercise of long-term bedridden patients. By studying Kelly’s physical changes in long-term space missions, NASA researchers are trying to find more effective ways to ensure the health of astronauts in long-term missions. At the beginning of the experiment, the research team at the University of Missouri isolated stem cells from adipose tissue and set up three experimental groups to determine which mechanism best helped to regenerate cells. One group simulated the microgravity environment, the other group simulated the stress load, and the third group was the control group. “What we have to do is reveal the effect of the appropriate stress load on the new cartilage tissue engineering and its necessity,” said Roberto. Using the drum bioreactor designed by NASA Johnson Space Center, the research team exposed a group of cultured stem cells to simulated microgravity environments; the other group placed under stress load conditions simulated by rotary pressure vessels; the last group was used as a control , That is only by the normal gravity of the Earth’s role. By observing the growth of these stem cells, the team found that the stress loading effect of simulated gravity had the best effect on stem cells. Additional stress, such as the pain of the cartilage in the body’s movement, is critical to the growth of chondrocytes. Schematic diagram of different experimental groups. One group of three experimental groups simulated the microgravity environment, the other group simulated the stress load, and the third group was the control group. “The stress stimulus of cyclic hydrostatic pressure (CHP) simulates the stress environment of cartilage on the daily activities of the earth, which is more conducive to the formation of cartilage than cells cultured in microgravity reactors, Researchers wrote in the paper. It seems that astronauts, if they can carry out their daily activities in a gravity-like environment, will make their bones and joints more healthy and more conducive to damage repair. The results of this study were published in the April issue of Aerospace Medicine and Human Health. (Any day)

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