The spindle-shaped fat precursor cells become more round after receiving the treatment of the dust extract. The number of blue (DNA) markers indicates an increase in the number of cells, and the yellow lipid staining shows fat. We can observe the cells in the various stages of development – some yellow lipid has basically occupied the entire cell space. Source: Christopher Cassidys second stand We all know that dust will stimulate us to sneeze, make the room dirty, but it can also harm us fat it? A recent paper published in Environmental Science and Technology shows that it is possible. Dust can cause metabolic disorders Previous study found that indoor dust mixed with dander, pollen and other small particles from the surrounding environment, but also contains endocrine disruptors or hormones that affect the body of chemical substances. Hormones are a chemical that helps regulate body function, and our fertility, mood changes, and body weight are affected by hormones. Duke University Nicholas Environmental College endocrinologist Christopher Cassidys is the author of the paper. In the previous study, the researchers found 41 kinds of chemical substances in the indoor dust samples. In this experiment, Cassidys and his colleagues used these substances, including phthalates – vinyl and other plastic products, plasticizers, p-hydroxybenzoate – widely used Preservatives in cosmetics and pharmaceuticals, and common household insecticides, such as permethrin, are designed to drive mosquitoes and ticks. The experimental model they use is called the mouse adipose precursor cell model. Researchers have tried to see if these chemicals can induce fat into cells to mature adipocytes. “This model is very reliable, as early as fifty years ago,” says Cassidys, “and the fat precursor cells are cells that have been differentiated in the laboratory for two weeks and are known as mature white fats Cells like these mature adipocytes will surround the periphery of the precursor cells and begin to proliferate. “If a chemical substance can induce precursor cells to produce such fat-like cells and make the number of cells more than the normal basis Value, there may be two reasons: either the precursor cell itself becomes larger, or precursor cells by stimulating rapid proliferation. Which indicates that chemical substances may promote cell storage of fat. Approximately two-thirds of the chemicals tested by the team of Cassidysis can trigger the transformation of precursor cells. In another experiment, Cassidys collected samples of indoor dust from 11 houses in central North Carolina. The inhabitants of these houses are kept for at least two years and at least 2 days before the sample is collected without vacuum cleaner cleaning. Yes, that’s what you think – the researchers tell the landlord, in the name of science, do not clean. The researchers then tested the extracts of these dust samples with the mouse fatty precursor cell model described above and found that 10 of the 11 samples could induce the transformation of the precursor cells into adipocytes. Cassidys argues that this suggests that dust causes a major health hazard – metabolic disorders, which may be more serious than what we thought before. Children are more sensitive to this finding, especially in families with children at home, parents need to pay more attention – children are often more sensitive to endocrine disrupting substances. The sensitive part of the reason is that the child is too weak to inhale the same dose for children and adults, and endocrine disruptions may have a greater impact on smaller children. An ordinary child crawls on the ground every day, the dirty fist and toys into his mouth, will inevitably inhalation of dust. The US Environmental Protection Agency has estimated the amount of dust that a child may inhale in his daily life. According to the above study, the average of these children’s dust inhalation is sufficient to elicit the fat transformation we observed in mouse cells. However, Jennifer Schleicher, an associate professor of environmental hygiene at the University of Boston School of Public Health, said the experiment has limitations, and the study of mouse cell levels is not equivalent to the case where humans are exposed directly to indoor dust. We walk around every day, the pollutants must be separated from the dust, through some way through the skin this protective barrier can be absorbed by the body – so only a part of the dust in the chemical substances really into the body. Researchers did not say that indoor dust was the cause of Americans, and even global humans (and rats in the laboratory) that became more and more fat. Subsequent studies will experiment with this issue, but not this time. “Because the fat precursor cell model is very reliable, we are well aware of it, so there is a lot of research to apply this experimental model to humans.” Epidemiological studies have shown that exposure to these The higher the degree of chemical substance, the more chaotic the body’s metabolism. We may not have direct evidence that the effects of chemical substances on mouse cells and its effects on the human body are the same, but the experimental results are now clearly pointing to this direction. Careful use of chemical cleaners These chemicals are the culprit of our fat, and it is too early to conclude. However, more and more studies, including the study, show that it is justified and necessary to minimize exposure to these endocrine disruptive chemicals. In order to do this, Cassidys recommends that homeowners often clean indoor hygiene, with wet mop and sprinkle the way to avoid dust accumulation. Of course, this removal method only use water or soap to play a role, do not use those chemical composition cleaning agent, it will only make the room chemical endocrine disruptors more and more. Cassidys also suggested avoiding the use of plastic containers as much as possible, especially not to use it to heat and store food. In the room less spray insecticide, these chemicals will stay in your house for a long time, so should be used with caution. Now more and more green personal care industry and furniture companies want to make money by clearing household chemicals, but be sure to check out whether those chemicals really harm you, and then completely remove it from your houseThe In addition, do not think that the home clean, you can give up a healthy diet and exercise. This is not to give you a meal to find an excuse for yo.