Get rid of Hwang ‘s scandal embrace gene editing technology


CRISPR-Cas9 technology may bring a wave of new technology, so that scientists in which adventure surfing. South Korean scientists have suggested that CRISPR-Cas9 technology may treat a range of diseases. Today, scientists have increased the pressure on the government, asked to relax the strict regulation of human embryos, ban”. A total of 11 researchers and academics were invited to discuss the impact of the country’s bioethical policy on research in the Seoul National Bioethics Committee and the Public Health and Welfare Forum held in Seoul. Participants believe that the relevant laws should be promoted as soon as possible to promote the Korean scientific community in the field of human embryos research, and the resulting new treatment methods to explore. “Nature” magazine on the matter to give attention. Starting in “Wrestling” In 2004, Wu Suhong, head of Seoul National University, claimed that human stem cells were produced from cloned human embryos. In response to an open debate, South Korea’s Bioethics and Biosecurity Act came into effect one year later, limiting human embryos research, and only those scientists who obtained licenses from the National Bioethics Committee were able to engage in this research. Initially, the Hwang team was the only one authorized. Then, in 2006, his results were found to be forged, and Hwang was also sentenced for corruption and bioethics. Although the provisions of the study of human embryos before the scandal was enacted, but many people believe that the new research work is therefore stagnant state, which is equivalent to the implementation of the Korean embryo research “de facto”. Only one team scandal, the only access to embryonic stem cell project research license, still only one, became the Seoul University development biologist Li Dongli led the research team. Li Dongli said that in South Korea, his team is limited to the use of low temperature frozen in vitro fertilization of the remaining eggs. However, it is particularly difficult to obtain stem cells from the obtained embryos by reducing the effectiveness of cloning techniques for inserting another human DNA with frozen eggs. Scientists are more inclined to use fresh eggs directly from donors, and South Korea’s laws force him to go abroad to study. In 2014, the Li Dongli team reported cloning of human embryonic stem cells, but in fact it was carried out at the CHA satellite facility in Los Angeles, California, using the American donor’s egg. At that time, the United States on embryonic stem cell research, not subject to federal law. Li Dongli hopes that South Korea’s law will be modified so that national researchers can get the donor’s fresh eggs. “The existing regulations are based on the most advanced gene editing technology CRISPR-Cas9,” said Kim Soo Soo, an engineer at the Korea Daejeon Foundation for Basic Sciences, who said at the forum. “In South Korea, this latest tool Can be used in cells other than the human body, but can not be used in embryos or human cells. “Kim Soo-soo, CRISPR-Cas9 technology may treat a series of diseases, in clinical and embryo testing are very useful. More importantly, many countries, including China, the United States, the United Kingdom and Sweden, have allowed genetic experiments on human embryos. Scientists believe that the lifting of the “ban”, not only to restore the use of Korean donors to the convenience of eggs, but also encourage scientists to study the East Asian population genetic disease development mechanism. Before the forum was held, local media reported that a group of government-organized researchers, ethicists and religious scholars was lobbying the government to end research restrictions on human embryos. But some bioethics have warned the government not to try to make a change in the law without public consultation. The Department of Health and Welfare’s Bioethics Department told the “Nature” magazine news team that there was no plan to modify the existing regulations. It may take several years to amend the rules, but the scientists believe that the opening of a public hearing is a big step towards this long journey. (Science & Technology Daily, Beijing, September 11)

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